One person was killed and at least six others injured by police fire when anti-US protesters clashed with security forces outside the US consulate in Karachi, Pakistan's largest city.
Police deployed water cannons, and fired tear gas and warning shots to disperse crowds of angry protesters, who threw rocks at the US consulate and set fire to a nearby police station.
Witnesses reported that protesters tore down the consulate's American flag.
Karachi's chief of police says 47 policemen were injured in clashes, with three of them in critical condition, Pakistani journalist Khalid Khan reports on Twitter.
The rally was organized by the Shia Muslim student organization Majlis Wahdat Muslimeen. After the clashes, the group announced that it would organize a large sit-in to protest the death of the protester, as well as the incendiary anti-Islamic movie.
Protesters held anti-US rallies in cities across Pakistan, demanding the expulsion of the US ambassador and calling for a boycott on all American goods and services, RT's Paula Slier reported.
On Sunday, hundreds of Afghan students held a protest rally in Kabul. Demonstrators chanted anti-US slogans, and burned an American flag and a poster of Barack Obama.
The film was simply the last straw for Muslim society, which was already fed up with US propaganda, Ahmed Quraishi, from the Paknationalists Forum, told RT.
“These demonstrations are not really directed at the film itself. They are result of accumulation. Over the past few months and years there has been an organized campaign to insult and humiliate Islam, particularly in the United States,” he explained.